技術(shù)文章
Technical articlesSynonyms:Shh,HHG-1Description:Hedgehog(Hh)proteinsarewidelydistributedthroughouttheanimalkingdomandplayimportantregulatoryrolesinvariousdevelopmentprocesses.ThethreeknownmammalianHhproteins,Sonic(Shh),Desert(Dhh)andIndian(Ihh)arestructurall...
【用途】本試劑盒用于定量測(cè)定人血清中妊娠相關(guān)血漿蛋白A(PAPP-A)的濃度。本實(shí)驗(yàn)僅用于體外診斷。【臨床意義】妊娠相關(guān)血漿蛋白A(PAPP-A)是由胎盤分泌的一種大分子糖蛋白。在妊娠期間,它由胚胎滋養(yǎng)層高濃度分泌并釋放到母親的血循環(huán)中。母親血清中的PAPP-A水平隨著妊娠周數(shù)的增加而升高,在足月時(shí)達(dá)到zui高峰。PAPP-A并不是妊娠*的,因?yàn)樵谖磻言械呐院湍行灾幸材軝z測(cè)出PAPP-A。在未懷孕的女性中,PAPP-A可能由子宮內(nèi)膜產(chǎn)生。zui近的研究表明,PAPP-A作為...
Synonyms:PlaetFactor-4,CXCL4,OncostatinA,IronplactDescription:PF-4isaCXCchemokinethatisexpressedinmegakaryocytesandstoredinthealpha-granulesofplaets.PF-4ischemotactictowardsneutrophilsandmonocytesandhasbeenshowntoinhibitangiogenesis.Recombi...
功能性基因組平臺(tái)技術(shù)因?yàn)槿狈玫氖侄窝芯縏Fs在體內(nèi)調(diào)節(jié)基因表達(dá)作用,目前研究的主流是基于體外的研究。Geneka正開發(fā)一種新的基于細(xì)胞水平的技術(shù)平臺(tái)來建立高通量篩選分析法和新的驗(yàn)證手段,以便能夠獲得在體內(nèi),各個(gè)組分作用于TFs介導(dǎo)的基因表達(dá)的具體分析數(shù)據(jù)。旨在描繪化學(xué)和生物分子作為臨床實(shí)驗(yàn)主要成分的治療潛能。此項(xiàng)技術(shù)可幫助藥廠和生物技術(shù)公司節(jié)約大量的錢,因?yàn)樗山档吞剿麇e(cuò)誤目標(biāo)的可能性,并且降低臨床實(shí)驗(yàn)所需的錢和時(shí)間。轉(zhuǎn)錄因子(TFs)綜述TFs在基因表達(dá)調(diào)控中起關(guān)鍵作用。...
Synonyms:MacrophageColonyStimulatingFactor,CSF-1,MGI-IMDescription:M-CSFisapotenthematopoieticfactorproducedbyavarietyofcellsincludinglymphocytes,monocytes,fibroblasts,endothelialcells,myoblastsandosteoblasts.Itisakeyregulatorofcellularprol...
Synonyms:noneDescription:IL-12isadisulfide-linkedheterodimericprotein(p70),composedoftwosubunits,p35andp40,whichareencodedbytwodifferentgenes.Accumulatingdataindicatethatp40secretionprecedesthatofIL-12expression.Inaddition,toitsabilitytocov...
Synonyms:Glial-DerivedNeurotrophicFactor,ATF-1Description:GDNFisadisulfide-linkedhomodimericneurotrophicfactorstructurallyrelatedtoArtemin,NeurturinandPersephin.Theseproteinsbelongtothecysteine-knotsuperfamilyofgrowthfactorsthatassumestable...
Synonyms:FibroblastGrowthFactor-basic,FGF-2,HBGF-2,ProstatropinDescription:FGF-basicisoneof23knownmembersoftheFGFfamily.Proteinsofthisfamilyplayacentralroleduringprenataldevelopmentandpostnatalgrowthandregenerationofavarietyoftissues,byprom...